Prion publications from our partners (2005-2006)

Published in 2006
Published in 2005

Updated on: 7th of September 2006

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Published in 2006

Acutis PL, Bossers A, Priem J, Riina MV, Peletto S, Mazza M, Casalone C, Forloni G, Ru G, Caramelli M: Identification of prion protein gene polymorphisms in goats from Italian scrapie outbreaks. J Gen Virol 2006, 87:1029-1033.

Acutis PL, Martucci F, Mazza M, Peletto S, Iulini B, Corona C, Bozzetta E, Casalone C, Caramelli M: A case of scrapie in a sheep carrying the lysine-171 allele of the prion protein gene. Arch Virol 2006, 151:1875-1880.

Adle-Biassette H, Verney C, Peoc'h K, Dauge MC, Razavi F, Choudat L, Gressens P, Budka H, Henin D: Immunohistochemical expression of prion protein (PrPC) in the human forebrain during development. J Neuropathol Exp Neurol 2006, 65:698-706.

Aguzzi A: Prion diseases of humans and farm animals: epidemiology, genetics, and pathogenesis. J Neurochem 2006, 97:1726-1739.

Aguzzi A, Glatzel M: Prion infections, blood and transfusions. Nat Clin Pract Neurol 2006, 2:321-329.

Andreoletti O, Morel N, Lacroux C, Rouillon V, Barc C, Tabouret G, Sarradin P, Berthon P, Bernardet P, Mathey J, Lugan S, Costes P, Corbiere F, Espinosa JC, Torres JM, Grassi J, Schelcher F, Lantier F: Bovine spongiform encephalopathy agent in spleen from an ARR/ARR orally exposed sheep. J Gen Virol 2006, 87:1043-1046.

Appel TR, Lucassen R, Groschup MH, Joncic M, Beekes M, Riesner D: Acid inactivation of prions: efficient at elevated temperature or high acid concentration. J Gen Virol 2006, 87:1385-1394.

Asante EA, Linehan JM, Gowland I, Joiner S, Fox K, Cooper S, Osiguwa O, Gorry M, Welch J, Houghton R, Desbruslais M, Brandner S, Wadsworth JD, Collinge J: Dissociation of pathological and molecular phenotype of variant Creutzfeldt-Jakob disease in transgenic human prion protein 129 heterozygous mice. Proc Natl Acad Sci U S A 2006, 103:10759-10764.

Barnewitz K, Maringer M, Mitteregger G, Giese A, Bertsch U, Kretzschmar HA: Unaltered prion protein cleavage in plasminogen-deficient mice. Neuroreport 2006, 17:527-530.

Baron T, Biacabe AG: Origin of bovine spongiform encephalopathy. Lancet 2006, 367:297-298; author reply 298-299.

Baron TG, Biacabe AG, Bencsik A, Langeveld JP: Transmission of new bovine prion to mice. Emerg Infect Dis 2006, 12:1125-1128.

Basset-Leobon C, Uro-Coste E, Peoc'h K, Haik S, Sazdovitch V, Rigal M, Andreoletti O, Hauw JJ, Delisle MB: Familial Creutzfeldt-Jakob disease with an R208H-129V haplotype and Kuru plaques. Arch Neurol 2006, 63:449-452.

Bate C, Kempster S, Last V, Williams A: Interferon-gamma increases neuronal death in response to amyloid-beta1-42. J Neuroinflammation 2006, 3:7.

Bate C, Kempster S, Williams A: Platelet-activating factor antagonists protect amyloid-beta damaged neurons from microglia-mediated death. Neuropharmacology 2006, 51:173-181.

Bate C, Kempster S, Williams A: Prostaglandin D2 mediates neuronal damage by amyloid-beta or prions which activates microglial cells. Neuropharmacology 2006, 50:229-237.

Bencsik AA, Coleman AW, Debeer SO, Perron H, Moussa A: Amplified immunohistochemical detection of PrPsc in animal transmissible spongiform encephalopathies using streptomycin. J Histochem Cytochem 2006, 54:849-853.

Berardi VA, Cardone F, Valanzano A, Lu M, Pocchiari M: Preparation of soluble infectious samples from scrapie-infected brain: a new tool to study the clearance of transmissible spongiform encephalopathy agents during plasma fractionation. Transfusion 2006, 46:652-658.

Biasini E, Massignan T, Fioriti L, Rossi V, Dossena S, Salmona M, Forloni G, Bonetto V, Chiesa R: Analysis of the cerebellar proteome in a transgenic mouse model of inherited prion disease reveals preclinical alteration of calcineurin activity. Proteomics 2006, 6:2823-2834.

Binelli S, Agazzi P, Giaccone G, Will RG, Bugiani O, Franceschetti S, Tagliavini F: Periodic electroencephalogram complexes in a patient with variant Creutzfeldt-Jakob disease. Ann Neurol 2006, 59:423-427.

Birkmann E, Schafer O, Weinmann N, Dumpitak C, Beekes M, Jackman R, Thorne L, Riesner D: Detection of prion particles in samples of BSE and scrapie by fluorescence correlation spectroscopy without proteinase K digestion. Biol Chem 2006, 387:95-102.

Bishop MT, Hart P, Aitchison L, Baybutt HN, Plinston C, Thomson V, Tuzi NL, Head MW, Ironside JW, Will RG, Manson JC: Predicting susceptibility and incubation time of human-to-human transmission of vCJD. Lancet Neurol 2006, 5:393-398.

Biswas S, Langeveld JP, Tipper D, Lu S: Intracellular accumulation of a 46kDa species of mouse prion protein as a result of loss of glycosylation in cultured mammalian cells. Biochem Biophys Res Commun 2006.

Bradley R, Collee JG, Liberski PP: Variant CJD (vCJD) and Bovine Spongiform Encephalopathy (BSE): 10 and 20 years on: part 1. Folia Neuropathol 2006, 44:93-101.

Buerger K, Otto M, Teipel SJ, Zinkowski R, Blennow K, DeBernardis J, Kerkman D, Schroder J, Schonknecht P, Cepek L, McCulloch C, Moller HJ, Wiltfang J, Kretzschmar H, Hampel H: Dissociation between CSF total tau and tau protein phosphorylated at threonine 231 in Creutzfeldt-Jakob disease. Neurobiol Aging 2006, 27:10-15.

Buschmann A, Gretzschel A, Biacabe AG, Schiebel K, Corona C, Hoffmann C, Eiden M, Baron T, Casalone C, Groschup MH: Atypical BSE in Germany-Proof of transmissibility and biochemical characterization. Vet Microbiol 2006.

Cali I, Castellani R, Yuan J, Al-Shekhlee A, Cohen ML, Xiao X, Moleres FJ, Parchi P, Zou WQ, Gambetti P: Classification of sporadic Creutzfeldt-Jakob disease revisited. Brain 2006, 129:2266-2277.

Caramelli M, Ru G, Acutis P, Forloni G: Prion diseases: current understanding of epidemiology and pathogenesis, and therapeutic advances. CNS Drugs 2006, 20:15-28.

Cardone F, Brown P, Meyer R, Pocchiari M: Inactivation of transmissible spongiform encephalopathy agents in food products by ultra high pressure-temperature treatment. Biochim Biophys Acta 2006, 1764:558-562.

Casalone C, Caramelli M, Crescio MI, Spencer YI, Simmons MM: BSE immunohistochemical patterns in the brainstem: a comparison between UK and Italian cases. Acta Neuropathol (Berl) 2006, 111:444-449.

Collee JG, Bradley R, Liberski PP: Variant CJD (vCJD) and Bovine Spongiform Encephalopathy (BSE): 10 and 20 years on: part 2. Folia Neuropathol 2006, 44:102-110.

Collinge J, Whitfield J, McKintosh E, Beck J, Mead S, Thomas DJ, Alpers MP: Kuru in the 21st century--an acquired human prion disease with very long incubation periods. Lancet 2006, 367:2068-2074.

Collins SJ, Sanchez-Juan P, Masters CL, Klug GM, van Duijn C, Poleggi A, Pocchiari M, Almonti S, Cuadrado-Corrales N, de Pedro-Cuesta J, Budka H, Gelpi E, Glatzel M, Tolnay M, Hewer E, Zerr I, Heinemann U, Kretszchmar HA, Jansen GH, Olsen E, Mitrova E, Alperovitch A, Brandel JP, Mackenzie J, Murray K, Will RG: Determinants of diagnostic investigation sensitivities across the clinical spectrum of sporadic Creutzfeldt-Jakob disease. Brain 2006, 129:2278-2287.

Cooper SA, Murray KL, Heath CA, Will RG, Knight RS: Sporadic Creutzfeldt-Jakob disease with cerebellar ataxia at onset in the United Kingdom. J Neurol Neurosurg Psychiatry 2006.

Corona C, Casalone C, Acutis PL, Crescio MI, Martucci F, Iulini B, Florio CL, Gazzuola P, Perfetti G, Bona C, Ru G, Caramelli M: Detection of pathological prion protein in the tongue of sheep infected with naturally occurring scrapie. Vet Res Commun 2006, 30 Suppl 1:239-240.

Cortelli P, Perani D, Montagna P, Gallassi R, Tinuper P, Federica P, Avoni P, Ferrillo F, Anchisi D, Moresco RM, Fazio F, Parchi P, Baruzzi A, Lugaresi E, Gambetti P: Pre-symptomatic diagnosis in fatal familial insomnia: serial neurophysiological and 18FDG-PET studies. Brain 2006, 129:668-675.

Crozet C, Vezilier J, Delfieu V, Nishimura T, Onodera T, Casanova D, Lehmann S, Beranger F: The truncated 23-230 form of the prion protein localizes to the nuclei of inducible cell lines independently of its nuclear localization signals and is not cytotoxic. Mol Cell Neurosci 2006, 32:315-323.

Dandoy-Dron F, Bogdanova A, Beringue V, Bailly Y, Tovey MG, Laude H, Dron M: Infection by ME7 prion is not modified in transgenic mice expressing the yeast chaperone Hsp104 in neurons. Neurosci Lett 2006, 405:181-185.

D'Angelo A, Maurella C, Bona C, Borrelli A, Caramelli M, Elena Careddu M, Jaggy A, Ru G: Assessment of clinical criteria to diagnose scrapie in Italy. Vet J 2006.

Didier A, Dietrich R, Steffl M, Gareis M, Groschup MH, Muller-Hellwig S, Martlbauer E, Amselgruber WM: Cellular Prion Protein in the Bovine Mammary Gland Is Selectively Expressed in Active Lactocytes. J Histochem Cytochem 2006.

Dimitri D, Jehel L, Durr A, Levy-Soussan M, Andreux V, Laplanche JL, Fossati P, Cohen D: Fatal familial insomnia presenting as psychosis in an 18-year-old man. Neurology 2006, 67:363-364.

Dron M, Bailly Y, Beringue V, Haeberle AM, Griffond B, Risold PY, Tovey MG, Laude H, Dandoy-Dron F: SCRG1, a Potential Marker of Autophagy in Transmissible Spongiform Encephalopathies. Autophagy 2006, 2:58-60.

Eiden M, Buschmann A, Kupfer L, Groschup MH: Synthetic prions. J Vet Med B Infect Dis Vet Public Health 2006, 53:251-256.

Espenes A, Press CM, Landsverk T, Tranulis MA, Aleksandersen M, Gunnes G, Benestad SL, Fuglestveit R, Ulvund MJ: Detection of PrP(Sc) in rectal biopsy and necropsy samples from sheep with experimental scrapie. J Comp Pathol 2006, 134:115-125.

Foster J, McKenzie C, Parnham D, Drummond D, Goldmann W, Stevenson E, Hunter N: Derivation of a scrapie-free sheep flock from the progeny of a flock affected by scrapie. Vet Rec 2006, 159:42-45.

Georgsson G, Tryggvason T, Jonasdottir AD, Gudmundsson S, Thorgeirsdottir S: Polymorphism of PRNP codons in the normal Icelandic population. Acta Neurol Scand 2006, 113:419-425.

Gilch S, Kehler C, Schatzl HM: The prion protein requires cholesterol for cell surface localization. Mol Cell Neurosci 2006, 31:346-353.

Gobbi M, Colombo L, Morbin M, Mazzoleni G, Accardo E, Vanoni M, Del Favero E, Cantu L, Kirschner DA, Manzoni C, Beeg M, Ceci P, Ubezio P, Forloni G, Tagliavini F, Salmona M: Gerstmann-Straussler-Scheinker disease amyloid protein polymerizes according to the "dock-and-lock" model. J Biol Chem 2006, 281:843-849.

Gossner A, Hunter N, Hopkins J: Role of lymph-borne cells in the early stages of scrapie agent dissemination from the skin. Vet Immunol Immunopathol 2006, 109:267-278.

Grobben AH, Steele PJ, Somerville RA, Taylor DM: Inactivation of transmissible spongiform encephalopathy agents during the manufacture of dicalcium phosphate from bone. Vet Rec 2006, 158:361-366.

Grobben AH, Steele PJ, Somerville RA, Taylor DM: Inactivation of BSE infectivity on chips of bone by autoclaving during the manufacture of gelatine. Vet Rec 2006, 158:94-96.

Gubbins S, Roden JA: Breeding programmes for TSE resistance in British sheep. II. Assessing the impact on the prevalence and incidence of scrapie. Prev Vet Med 2006, 73:17-31.

Halimi M, Dayan-Amouyal Y, Kariv-Inbal Z, Friedman-Levi Y, Mayer-Sonnenfeld T, Gabizon R: Prion urine comprises a glycosaminoglycan-light chain IgG complex that can be stained by Congo red. J Virol Methods 2006, 133:205-210.

Heath CA, Barker RA, Esmonde TF, Harvey P, Roberts R, Trend P, Head MW, Smith C, Bell JE, Ironside JW, Will RG, Knight RS: Dura mater-associated Creutzfeldt-Jakob disease: experience from surveillance in the UK. J Neurol Neurosurg Psychiatry 2006, 77:880-882.

Hicks MR, Gill AC, Bath IK, Rullay AK, Sylvester ID, Crout DH, Pinheiro TJ: Synthesis and structural characterization of a mimetic membrane-anchored prion protein. Febs J 2006, 273:1285-1299.

Hill AF, Joiner S, Beck JA, Campbell TA, Dickinson A, Poulter M, Wadsworth JD, Collinge J: Distinct glycoform ratios of protease resistant prion protein associated with PRNP point mutations. Brain 2006, 129:676-685.

Hortells P, Monzon M, Monleon E, Acin C, Vargas A, Bolea R, Lujan L, Badiola JJ: Pathological findings in retina and visual pathways associated to natural Scrapie in sheep. Brain Res 2006.

Ierna M, Farquhar CF, Outram GW, Bruce ME: Resistance of neonatal mice to scrapie is associated with inefficient infection of the immature spleen. J Virol 2006, 80:474-482.

Ingrosso L, Novoa B, Valle AZ, Cardone F, Aranguren R, Sbriccoli M, Bevivino S, Iriti M, Liu Q, Vetrugno V, Lu M, Faoro F, Ciappellano S, Figueras A, Pocchiari M: Scrapie infectivity is quickly cleared in tissues of orally-infected farmed fish. BMC Vet Res 2006, 2:21.

Jeffrey M, Gonzalez L, Chong A, Foster J, Goldmann W, Hunter N, Martin S: Ovine infection with the agents of scrapie (CH1641 isolate) and bovine spongiform encephalopathy: immunochemical similarities can be resolved by immunohistochemistry. J Comp Pathol 2006, 134:17-29.

Jeffrey M, Martin S, Gonzalez L, Foster J, Langeveld JP, van Zijderveld FG, Grassi J, Hunter N: Immunohistochemical features of PrP(d) accumulation in natural and experimental goat transmissible spongiform encephalopathies. J Comp Pathol 2006, 134:171-181.

Kirchmayr R, Reichl HE, Schildorfer H, Braun R, Somerville RA: Prion protein: detection in 'spiked' anaerobic sludge and degradation experiments under anaerobic conditions. Water Sci Technol 2006, 53:91-98.

Krasnianski A, Meissner B, Schulz-Schaeffer W, Kallenberg K, Bartl M, Heinemann U, Varges D, Kretzschmar HA, Zerr I: Clinical features and diagnosis of the MM2 cortical subtype of sporadic Creutzfeldt-Jakob disease. Arch Neurol 2006, 63:876-880.

Krasnianski A, Schulz-Schaeffer WJ, Kallenberg K, Meissner B, Collie DA, Roeber S, Bartl M, Heinemann U, Varges D, Kretzschmar HA, Zerr I: Clinical findings and diagnostic tests in the MV2 subtype of sporadic CJD. Brain 2006, 129:2288-2296.

Krebs B, Dorner-Ciossek C, Schmalzbauer R, Vassallo N, Herms J, Kretzschmar HA: Prion protein induced signaling cascades in monocytes. Biochem Biophys Res Commun 2006, 340:13-22.

Krebs B, Kohlmannsperger V, Nolting S, Schmalzbauer R, Kretzschmar HA: A method to perform Western blots of microscopic areas of histological sections. J Histochem Cytochem 2006, 54:559-565.

Kretlow A, Wang Q, Kneipp J, Lasch P, Beekes M, Miller L, Naumann D: FTIR-microspectroscopy of prion-infected nervous tissue. Biochim Biophys Acta 2006, 1758:948-959.

Landolt HP, Glatzel M, Blattler T, Achermann P, Roth C, Mathis J, Weis J, Tobler I, Aguzzi A, Bassetti CL: Sleep-wake disturbances in sporadic Creutzfeldt-Jakob disease. Neurology 2006, 66:1418-1424.

Langeveld JP, Jacobs JG, Erkens JH, Bossers A, van Zijderveld FG, van Keulen LJ: Rapid and discriminatory diagnosis of scrapie and BSE in retro-pharyngeal lymph nodes of sheep. BMC Vet Res 2006, 2:19.

Leblanc P, Alais S, Porto-Carreiro I, Lehmann S, Grassi J, Raposo G, Darlix JL: Retrovirus infection strongly enhances scrapie infectivity release in cell culture. Embo J 2006, 25:2674-2685.

Lewis PA, Properzi F, Prodromidou K, Clarke AR, Collinge J, Jackson GS: Removal of the glycosylphosphatidylinositol anchor from PrP(Sc) by cathepsin D does not reduce prion infectivity. Biochem J 2006, 395:443-448.

Lewis PA, Tattum MH, Jones S, Bhelt D, Batchelor M, Clarke AR, Collinge J, Jackson GS: Codon 129 polymorphism of the human prion protein influences the kinetics of amyloid formation. J Gen Virol 2006, 87:2443-2449.

Lezmi S, Bencsik A, Baron T: PET-blot Analysis Contributes to BSE Strain Recognition in C57Bl/6 Mice. J Histochem Cytochem 2006.

Lezmi S, Ronzon F, Bencsik A, Bedin A, Calavas D, Richard Y, Simon S, Grassi J, Baron T: PrP(d) accumulation in organs of ARQ/ARQ sheep experimentally infected with BSE by peripheral routes. Acta Biochim Pol 2006, 53:399-405.

Linguraru MG, Ayache N, Bardinet E, Ballester MA, Galanaud D, Haik S, Faucheux B, Hauw JJ, Cozzone P, Dormont D, Brandel JP: Differentiation of sCJD and vCJD forms by automated analysis of basal ganglia intensity distribution in multisequence MRI of the brain--definition and evaluation of new MRI-based ratios. IEEE Trans Med Imaging 2006, 25:1052-1067.

Lipscomb IP, Sihota AK, Botham M, Harris KL, Keevil CW: Rapid method for the sensitive detection of protein contamination on surgical instruments. J Hosp Infect 2006, 62:141-148.

Lipscomb IP, Sihota AK, Keevil CW: Diathermy forceps and pencils: reservoirs for protein and prion contamination? J Hosp Infect 2006.

Luhken G, Brandt HR, Buschmann A, Groschup MH, Erhardt G: Microsatellite CTSBJ12 is located distal to the ovine prion protein gene on OAR13 and is not associated with scrapie susceptibility. Anim Genet 2006, 37:426-427.

Lyahyai J, Bolea R, Serrano C, Monleon E, Moreno C, Osta R, Zaragoza P, Badiola JJ, Martin-Burriel I: Correlation between Bax overexpression and prion deposition in medulla oblongata from natural scrapie without evidence of apoptosis. Acta Neuropathol (Berl) 2006.

Mabbott NA, MacPherson GG: Prions and their lethal journey to the brain. Nat Rev Microbiol 2006, 4:201-211.

McIntyre KM, Gubbins S, Goldmann W, Stevenson E, Baylis M: The time-course of a scrapie outbreak. BMC Vet Res 2006, 2:20.

Mead S, Poulter M, Beck J, Webb TE, Campbell TA, Linehan JM, Desbruslais M, Joiner S, Wadsworth JD, King A, Lantos P, Collinge J: Inherited prion disease with six octapeptide repeat insertional mutation--molecular analysis of phenotypic heterogeneity. Brain 2006, 129:2297-2317.

Milhavet O, Casanova D, Chevallier N, McKay RD, Lehmann S: Neural stem cell model for prion propagation. Stem Cells 2006.

Monaco S, Zanusso G, Mazzucco S, Rizzuto N: Cerebral amyloidoses: molecular pathways and therapeutic challenges. Curr Med Chem 2006, 13:1903-1913.

Morignat E, Cazeau G, Biacabe AG, Vinard JL, Bencsik A, Madec JY, Ducrot C, Baron T, Calavas D: Estimates of the prevalence of transmissible spongiform encephalopathies in sheep and goats in France in 2002. Vet Rec 2006, 158:683-687.

Moroncini G, Mangieri M, Morbin M, Mazzoleni G, Ghetti B, Gabrielli A, Williamson RA, Giaccone G, Tagliavini F: Pathologic prion protein is specifically recognized in situ by a novel PrP conformational antibody. Neurobiol Dis 2006, 23:717-724.

Muller-Hellwig S, Groschup MH, Pichner R, Gareis M, Martlbauer E, Scherer S, Loessner MJ: Biochemical evidence for the proteolytic degradation of infectious prion protein PrPsc in hamster brain homogenates by foodborne bacteria. Syst Appl Microbiol 2006, 29:165-171.

Murdoch H, Taylor D, Dickinson J, Walker JT, Perrett D, Raven ND, Sutton JM: Surface decontamination of surgical instruments: an ongoing dilemma. J Hosp Infect 2006, 63:432-438.

Nonno R, Bari MA, Cardone F, Vaccari G, Fazzi P, Dell'omo G, Cartoni C, Ingrosso L, Boyle A, Galeno R, Sbriccoli M, Lipp HP, Bruce M, Pocchiari M, Agrimi U: Efficient transmission and characterization of creutzfeldt-jakob disease strains in bank voles. PLoS Pathog 2006, 2:e12.

Peoc'h K, Delasnerie-Laupretre N, Beaudry P, Laplanche JL: Diagnostic value of CSF 14-3-3 detection in sporadic CJD diagnosis according to the age of the patient. Eur J Neurol 2006, 13:427-428.

Piening N, Nonno R, Di Bari M, Walter S, Windl O, Agrimi U, Kretzschmar HA, Bertsch U: Conversion efficiency of bank vole prion protein in vitro is determined by residues 155 and 170, but does not correlate with the high susceptibility of bank voles to sheep scrapie in vivo. J Biol Chem 2006, 281:9373-9384.

Piening N, Weber P, Hogen T, Beekes M, Kretzschmar H, Giese A: Photo-induced crosslinking of prion protein oligomers and prions. Amyloid 2006, 13:67-77.

Piubelli C, Fiorini M, Zanusso G, Milli A, Fasoli E, Monaco S, Righetti PG: Searching for markers of Creutzfeldt-Jakob disease in cerebrospinal fluid by two-dimensional mapping. Proteomics 2006, 6 Suppl 1:S256-261.

Preusser M, Strobel T, Gelpi E, Eiler M, Broessner G, Schmutzhard E, Budka H: Alzheimer-type neuropathology in a 28 year old patient with iatrogenic Creutzfeldt-Jakob disease after dural grafting. J Neurol Neurosurg Psychiatry 2006, 77:413-416.

Priola SA, Vorberg I: Molecular aspects of disease pathogenesis in the transmissible spongiform encephalopathies. Mol Biotechnol 2006, 33:71-88.

Raymond GJ, Olsen EA, Lee KS, Raymond LD, Bryant PK, 3rd, Baron GS, Caughey WS, Kocisko DA, McHolland LE, Favara C, Langeveld JP, van Zijderveld FG, Mayer RT, Miller MW, Williams ES, Caughey B: Inhibition of protease-resistant prion protein formation in a transformed deer cell line infected with chronic wasting disease. J Virol 2006, 80:596-604.

Ricchelli F, Buggio R, Drago D, Salmona M, Forloni G, Negro A, Tognon G, Zatta P: Aggregation/fibrillogenesis of recombinant human prion protein and Gerstmann-Straussler-Scheinker disease peptides in the presence of metal ions. Biochemistry 2006, 45:6724-6732.

Rigou P, Rezaei H, Grosclaude J, Staunton S, Quiquampoix H: Fate of prions in soil: adsorption and extraction by electroelution of recombinant ovine prion protein from montmorillonite and natural soils. Environ Sci Technol 2006, 40:1497-1503.

Rivera-Milla E, Oidtmann B, Panagiotidis CH, Baier M, Sklaviadis T, Hoffmann R, Zhou Y, Solis GP, Stuermer CA, Malaga-Trillo E: Disparate evolution of prion protein domains and the distinct origin of Doppel- and prion-related loci revealed by fish-to-mammal comparisons. Faseb J 2006, 20:317-319.

Roden JA, Nieuwhof GJ, Bishop SC, Jones DA, Haresign W, Gubbins S: Breeding programmes for TSE resistance in British sheep. I. Assessing the impact on prion protein (PrP) genotype frequencies. Prev Vet Med 2006, 73:1-16.

Rodriguez A, Perez-Gracia E, Espinosa JC, Pumarola M, Torres JM, Ferrer I: Increased expression of water channel aquaporin 1 and aquaporin 4 in Creutzfeldt-Jakob disease and in bovine spongiform encephalopathy-infected bovine-PrP transgenic mice. Acta Neuropathol (Berl) 2006.

Salguero FJ, Diaz-San SF, Brun A, Cano MJ, Torres JM: Comparison of three monoclonal antibodies for use in immunohistochemical detection of bovine spongiform encephalopathy protease-resistant prion protein. J Vet Diagn Invest 2006, 18:106-109.

Sanchez-Juan P, Green A, Ladogana A, Cuadrado-Corrales N, Saanchez-Valle R, Mitrovaa E, Stoeck K, Sklaviadis T, Kulczycki J, Hess K, Bodemer M, Slivarichova D, Saiz A, Calero M, Ingrosso L, Knight R, Janssens AC, van Duijn CM, Zerr I: CSF tests in the differential diagnosis of Creutzfeldt-Jakob disease. Neurology 2006, 67:637-643.

Scherbel C, Pichner R, Groschup MH, Mueller-Hellwig S, Scherer S, Dietrich R, Maertlbauer E, Gareis M: Degradation of scrapie associated prion protein (PrP(Sc)) by the gastrointestinal microbiota of cattle. Vet Res 2006, 37:695-703.

Schettler E, Steinbach F, Eschenbacher-Kaps I, Gerst K, Muessdoerffer F, Risch K, Streich WJ, Frolich K: Surveillance for prion disease in cervids, Germany. Emerg Infect Dis 2006, 12:319-322.

Schoch G, Seeger H, Bogousslavsky J, Tolnay M, Janzer RC, Aguzzi A, Glatzel M: Analysis of prion strains by PrPSc profiling in sporadic Creutzfeldt-Jakob disease. PLoS Med 2006, 3:e14.

Serres C, Peoc'h K, Courtot AM, Lesaffre C, Jouannet P, Laplanche JL: Spatio-developmental distribution of the prion-like protein doppel in Mammalian testis: a comparative analysis focusing on its presence in the acrosome of spermatids. Biol Reprod 2006, 74:816-823.

Siso S, Gonzalez L, Houston F, Hunter N, Martin S, Jeffrey M: The neuropathologic phenotype of experimental ovine BSE is maintained after blood transfusion. Blood 2006, 108:745-748.

Spassov S, Beekes M, Naumann D: Structural differences between TSEs strains investigated by FT-IR spectroscopy. Biochim Biophys Acta 2006, 1760:1138-1149.

St Rose SG, Hunter N, Matthews L, Foster JD, Chase-Topping ME, Kruuk LE, Shaw DJ, Rhind SM, Will RG, Woolhouse ME: Comparative evidence for a link between Peyer's patch development and susceptibility to transmissible spongiform encephalopathies. BMC Infect Dis 2006, 6:5.

Stack M, Jeffrey M, Gubbins S, Grimmer S, Gonzalez L, Martin S, Chaplin M, Webb P, Simmons M, Spencer Y, Bellerby P, Hope J, Wilesmith J, Matthews D: Monitoring for bovine spongiform encephalopathy in sheep in Great Britain, 1998-2004. J Gen Virol 2006, 87:2099-2107.

Stengel A, Bach C, Vorberg I, Frank O, Gilch S, Lutzny G, Seifarth W, Erfle V, Maas E, Schatzl H, Leib-Mosch C, Greenwood AD: Prion infection influences murine endogenous retrovirus expression in neuronal cells. Biochem Biophys Res Commun 2006, 343:825-831.

Sutton JM, Dickinson J, Walker JT, Raven ND: Methods to minimize the risks of creutzfeldt-jakob disease transmission by surgical procedures: where to set the standard? Clin Infect Dis 2006, 43:757-764.

Takemura K, Wang P, Vorberg I, Surewicz W, Priola SA, Kanthasamy A, Pottathil R, Chen SG, Sreevatsan S: DNA aptamers that bind to PrP(C) and not PrP(Sc) show sequence and structure specificity. Exp Biol Med (Maywood) 2006, 231:204-214. Erratum in: Exp Biol Med (Maywood). 2006 Apr;231(4):485.

Tattum MH, Cohen-Krausz S, Khalili-Shirazi A, Jackson GS, Orlova EV, Collinge J, Clarke AR, Saibil HR: Elongated oligomers assemble into mammalian PrP amyloid fibrils. J Mol Biol 2006, 357:975-985.

Thomzig A, Cardone F, Kruger D, Pocchiari M, Brown P, Beekes M: Pathological prion protein in muscles of hamsters and mice infected with rodent-adapted BSE or vCJD. J Gen Virol 2006, 87:251-254.

Touzeau S, Chase-Topping ME, Matthews L, Lajous D, Eychenne F, Hunter N, Foster JD, Simm G, Elsen JM, Woolhouse ME: Modelling the spread of scrapie in a sheep flock: evidence for increased transmission during lambing seasons. Arch Virol 2006, 151:735-751.

Trevitt CR, Collinge J: A systematic review of prion therapeutics in experimental models. Brain 2006, 129:2241-2265.

Tribouillard D, Bach S, Gug F, Desban N, Beringue V, Andrieu T, Dormont D, Galons H, Laude H, Vilette D, Blondel M: Using budding yeast to screen for anti-prion drugs. Biotechnol J 2006, 1:58-67.

Tsiroulnikov K, Chobert JM, Haertle T: Copper-dependent degradation of recombinant ovine prion protein. Phosphatidylinositol stimulates aggregation and copper-driven disappearance of prion protein. Febs J 2006, 273:1959-1965.

Tsiroulnikov K, Rezaei H, Dalgalarrondo M, Chobert JM, Grosclaude J, Haertle T: Cu(II) induces small-size aggregates with amyloid characteristics in two alleles of recombinant ovine prion proteins. Biochim Biophys Acta 2006, 1764:1218-1226.

Unterberger U, Hoftberger R, Gelpi E, Flicker H, Budka H, Voigtlander T: Endoplasmic reticulum stress features are prominent in Alzheimer disease but not in prion diseases in vivo. J Neuropathol Exp Neurol 2006, 65:348-357.

Vargas F, Lujan L, Bolea R, Monleon E, Martin-Burriel I, Fernandez A, De Blas I, Badiola JJ: Detection and clinical evolution of scrapie in sheep by 3rd eyelid biopsy. J Vet Intern Med 2006, 20:187-193.

Verity CM, Winstone AM, Stellitano L, Nicoll A, Will RG: No clinical evidence of hidden vCJD in UK children. Arch Dis Child 2006, 91:608-609.

Vidal E, Bolea R, Tortosa R, Costa C, Domenech A, Monleon E, Vargas A, Badiola JJ, Pumarola M: Assessment of calcium-binding proteins (Parvalbumin and Calbindin D-28K) and perineuronal nets in normal and scrapie-affected adult sheep brains. J Virol Methods 2006, 136:137-146.

Vogelgesang S, Glatzel M, Walker LC, Kroemer HK, Aguzzi A, Warzok RW: Cerebrovascular P-glycoprotein expression is decreased in Creutzfeldt-Jakob disease. Acta Neuropathol (Berl) 2006, 111:436-443.

Voigtlander T, Unterberger U, Touma C, Palme R, Polster B, Strohschneider M, Dorner S, Budka H: Prominent corticosteroid disturbance in experimental prion disease. Eur J Neurosci 2006, 23:2723-2730.

Wadsworth JD, Joiner S, Fox K, Linehan JM, Desbruslais M, Brandner S, Asante EA, Collinge J: Prion infectivity in vCJD rectum. Gut 2006.

Wadsworth JD, Joiner S, Linehan JM, Cooper S, Powell C, Mallinson G, Buckell J, Gowland I, Asante EA, Budka H, Brandner S, Collinge J: Phenotypic heterogeneity in inherited prion disease (P102L) is associated with differential propagation of protease-resistant wild-type and mutant prion protein. Brain 2006, 129:1557-1569.

Waldman AD, Cordery RJ, Macmanus DG, Godbolt A, Collinge J, Rossor MN: Regional brain metabolite abnormalities in inherited prion disease and asymptomatic gene carriers demonstrated in vivo by quantitative proton magnetic resonance spectroscopy. Neuroradiology 2006, 48:428-433.

Ward HJ, Everington D, Cousens SN, Smith-Bathgate B, Leitch M, Cooper S, Heath C, Knight RS, Smith PG, Will RG: Risk factors for variant Creutzfeldt-Jakob disease: a case-control study. Ann Neurol 2006, 59:111-120.

Wells MA, Jackson GS, Jones S, Hosszu LL, Craven CJ, Clarke AR, Collinge J, Waltho JP: A reassessment of copper (II) binding in the full-length prion protein. Biochem J 2006.

Whittle IR, Knight RS, Will RG: Unsuccessful intraventricular pentosan polysulphate treatment of variant Creutzfeldt-Jakob disease. Acta Neurochir (Wien) 2006, 148:677-679; discussion 679.

Yull HM, Ritchie DL, Langeveld JP, van Zijderveld FG, Bruce ME, Ironside JW, Head MW: Detection of type 1 prion protein in variant Creutzfeldt-Jakob disease. Am J Pathol 2006, 168:151-157.

Zawlik I, Witusik M, Hulas-Bigoszewska K, Piaskowski S, Szybka M, Golanska E, Liberski PP, Rieske P: Regulation of PrPC expression: nerve growth factor (NGF) activates the prion gene promoter through the MEK1 pathway in PC12 cells. Neurosci Lett 2006, 400:58-62.

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Published in 2005

Adori C, Kovacs GG, Low P, Molnar K, Gorbea C, Fellinger E, Budka H, Mayer RJ, Laszlo L: The ubiquitin-proteasome system in Creutzfeldt-Jakob and Alzheimer disease: intracellular redistribution of components correlates with neuronal vulnerability. Neurobiol Dis 2005, 19:427-435.

Aguzzi A: Cell biology. Prion toxicity: all sail and no anchor. Science 2005, 308:1420-1421.

Aguzzi A, Heikenwalder M: Prions, cytokines, and chemokines: a meeting in lymphoid organs. Immunity 2005, 22:145-154.

Albrecht R, Krebs B, Reusche E, Nagel M, Lencer R, Kretzschmar HA: Signs of rapidly progressive dementia in a case of intravascular lymphomatosis. Eur Arch Psychiatry Clin Neurosci 2005, 255:232-235.

Arima K, Nishida N, Sakaguchi S, Shigematsu K, Atarashi R, Yamaguchi N, Yoshikawa D, Yoon J, Watanabe K, Kobayashi N, Mouillet-Richard S, Lehmann S, Katamine S: Biological and biochemical characteristics of prion strains conserved in persistently infected cell cultures. J Virol 2005, 79:7104-7112.

Baron T, Calavas D: [Bovine spongiform encephalopathy]. Pathol Biol (Paris) 2005, 53:229-236.

Barret A, Forestier L, Deslys JP, Julien R, Gallet PF: Glycosylation-related gene expression in prion diseases: PrPSc accumulation in scrapie infected GT1 cells depends on beta-1,4-linked GalNAc-4-SO4 hyposulfation. J Biol Chem 2005, 280:10516-10523.

Barron RM, Baybutt H, Tuzi NL, McCormack J, King D, Moore RC, Melton DW, Manson JC: Polymorphisms at codons 108 and 189 in murine PrP play distinct roles in the control of scrapie incubation time. J Gen Virol 2005, 86:859-868.

Baskakov I, Disterer P, Breydo L, Shaw M, Gill A, James W, Tahiri-Alaoui A: The presence of valine at residue 129 in human prion protein accelerates amyloid formation. FEBS Lett 2005, 579:2589-2596.

Bate C, Boshuizen R, Williams A: Microglial cells kill prion-damaged neurons in vitro by a CD14-dependent process. J Neuroimmunol 2005, 170:62-70.

Bencsik A, Philippe S, Vial L, Calavas D, Baron T: Automatic quantitation of vacuolar lesions in the brain of mice infected with transmissible spongiform encephalopathies. J Virol Methods 2005, 124:197-202.

Bencsik AA, Debeer SO, Baron TG: An alternative pretreatment procedure in animal transmissible spongiform encephalopathies diagnosis using PrPsc immunohistochemistry. J Histochem Cytochem 2005, 53:1199-1202.

Bertsch U, Winklhofer KF, Hirschberger T, Bieschke J, Weber P, Hartl FU, Tavan P, Tatzelt J, Kretzschmar HA, Giese A: Systematic identification of antiprion drugs by high-throughput screening based on scanning for intensely fluorescent targets. J Virol 2005, 79:7785-7791.

Bilkova Z, Castagna A, Zanusso G, Farinazzo A, Monaco S, Damoc E, Przybylski M, Benes M, Lenfeld J, Viovy JL, Righetti PG: Immunoaffinity reactors for prion protein qualitative analysis. Proteomics 2005, 5:639-647.

Bleich S, Otto M, Zerr I, Kropp S, Kretzschmar HA, Wiltfang J: Creutzfeldt-Jakob disease and homocysteine levels in plasma and cerebrospinal fluid. Gerontology 2005, 51:142-144.

Bocharova OV, Breydo L, Salnikov VV, Gill AC, Baskakov IV: Synthetic prions generated in vitro are similar to a newly identified subpopulation of PrPSc from sporadic Creutzfeldt-Jakob Disease. Protein Sci 2005, 14:1222-1232.

Boesenberg C, Schulz-Schaeffer WJ, Meissner B, Kallenberg K, Bartl M, Heinemann U, Krasnianski A, Stoeck K, Varges D, Windl O, Kretzschmar HA, Zerr I: Clinical course in young patients with sporadic Creutzfeldt-Jakob disease. Ann Neurol 2005, 58:533-543.

Bolea R, Monleon E, Schiller I, Raeber AJ, Acin C, Monzon M, Martin-Burriel I, Struckmeyer T, Oesch B, Badiola JJ: Comparison of immunohistochemistry and two rapid tests for detection of abnormal prion protein in different brain regions of sheep with typical scrapie. J Vet Diagn Invest 2005, 17:467-469.

Brown AR, Rebus S, McKimmie CS, Robertson K, Williams A, Fazakerley JK: Gene expression profiling of the preclinical scrapie-infected hippocampus. Biochem Biophys Res Commun 2005, 334:86-95.

Brugere-Picoux J, Adjou K, Brugere H: [Update on transmissible spongiform subacute encephalopathies (TSSE)]. Bull Acad Natl Med 2005, 189:389-398.

Buschmann A, Groschup MH: TSE eradication in small ruminants--quo vadis? Berl Munch Tierarztl Wochenschr 2005, 118:365-371.

Buschmann A, Groschup MH: Highly bovine spongiform encephalopathy-sensitive transgenic mice confirm the essential restriction of infectivity to the nervous system in clinically diseased cattle. J Infect Dis 2005, 192:934-942.

Cancellotti E, Wiseman F, Tuzi NL, Baybutt H, Monaghan P, Aitchison L, Simpson J, Manson JC: Altered glycosylated PrP proteins can have different neuronal trafficking in brain but do not acquire scrapie-like properties. J Biol Chem 2005, 280:42909-42918.

Capellari S, Cardone F, Notari S, Schinina ME, Maras B, Sita D, Baruzzi A, Pocchiari M, Parchi P: Creutzfeldt-Jakob disease associated with the R208H mutation in the prion protein gene. Neurology 2005, 64:905-907.

Cardinale A, Filesi I, Vetrugno V, Pocchiari M, Sy MS, Biocca S: Trapping prion protein in the endoplasmic reticulum impairs PrPC maturation and prevents PrPSc accumulation. J Biol Chem 2005, 280:685-694.

Carmona P, Monzon M, Monleon E, Badiola JJ, Monreal J: In vivo detection of scrapie cases from blood by infrared spectroscopy. J Gen Virol 2005, 86:3425-3431.

Cartoni C, Schinina ME, Maras B, Nonno R, Vaccari G, Di Baria MA, Conte M, Liu QG, Lu M, Cardone F, Windl O, Pocchiari M, Agrimi U: Identification of the pathological prion protein allotypes in scrapie-infected heterozygous bank voles (Clethrionomys glareolus) by high-performance liquid chromatography-mass spectrometry. J Chromatogr A 2005, 1081:122-126.

Casalone C, Corona C, Crescio MI, Martucci F, Mazza M, Ru G, Bozzetta E, Acutis PL, Caramelli M: Pathological prion protein in the tongues of sheep infected with naturally occurring scrapie. J Virol 2005, 79:5847-5849.

Castilla J, Brun A, Diaz-San Segundo F, Salguero FJ, Gutierrez-Adan A, Pintado B, Ramirez MA, del Riego L, Torres JM: Vertical transmission of bovine spongiform encephalopathy prions evaluated in a transgenic mouse model. J Virol 2005, 79:8665-8668.

Castilla J, Gutierrez-Adan A, Brun A, Pintado B, Salguero FJ, Parra B, Segundo FD, Ramirez MA, Rabano A, Cano MJ, Torres JM: Transgenic mice expressing bovine PrP with a four extra repeat octapeptide insert mutation show a spontaneous, non-transmissible, neurodegenerative disease and an expedited course of BSE infection. FEBS Lett 2005, 579:6237-6246.

Cepek L, Steinacker P, Mollenhauer B, Wiese B, Ciesielczyk B, Bibl M, Wiltfang J, Zerr I, Schulz-Schaeffer W, Kretzschmar HA, Poser S, Otto M: Follow-up investigations of tau protein and S-100B levels in cerebrospinal fluid of patients with Creutzfeldt-Jakob disease. Dement Geriatr Cogn Disord 2005, 19:376-382.

Chase-Topping ME, Kruuk LE, Lajous D, Touzeau S, Matthews L, Simm G, Foster JD, Rupp R, Eychenne F, Hunter N, Elsen JM, Woolhouse ME: Genotype-level variation in lifetime breeding success, litter size and survival of sheep in scrapie-affected flocks. J Gen Virol 2005, 86:1229-1238.

Collinge J: Molecular neurology of prion disease. J Neurol Neurosurg Psychiatry 2005, 76:906-919.

Conti S, Masocco M, Solimini R, Toccaceli V, Vichi M, Ladogana A, Almonti S, Puopolo M, Pocchiari M: [Creutzfeldt-Jakob disease and other human forms of transmissible spongiform encephalopathy in Italy: a mortality study carried out from different data sources]. Ann Ist Super Sanita 2005, 41:103-111.

Conti S, Masocco M, Toccaceli V, Vichi M, Ladogana A, Almonti S, Puopolo M, Pocchiari M: Mortality from human transmissible spongiform encephalopathies: a record linkage study. Neuroepidemiology 2005, 24:214-220.

Cooper SA, Murray KL, Heath CA, Will RG, Knight RS: Isolated visual symptoms at onset in sporadic Creutzfeldt-Jakob disease: the clinical phenotype of the "Heidenhain variant". Br J Ophthalmol 2005, 89:1341-1342.

Cordery RJ, Alner K, Cipolotti L, Ron M, Kennedy A, Collinge J, Rossor MN: The neuropsychology of variant CJD: a comparative study with inherited and sporadic forms of prion disease. J Neurol Neurosurg Psychiatry 2005, 76:330-336.

Criado JR, Sanchez-Alavez M, Conti B, Giacchino JL, Wills DN, Henriksen SJ, Race R, Manson JC, Chesebro B, Oldstone MB: Mice devoid of prion protein have cognitive deficits that are rescued by reconstitution of PrP in neurons. Neurobiol Dis 2005, 19:255-265.

Darbord JC, Hauw JJ: [Hospital practice and prion risks]. Pathol Biol (Paris) 2005, 53:237-243.

Deslys JP, Grassi J: [Screening tests for animal TSE: present and future]. Pathol Biol (Paris) 2005, 53:221-228.

Donofrio G, Heppner FL, Polymenidou M, Musahl C, Aguzzi A: Paracrine inhibition of prion propagation by anti-PrP single-chain Fv miniantibodies. J Virol 2005, 79:8330-8338.

Dron M, Bailly Y, Beringue V, Haeberle AM, Griffond B, Risold PY, Tovey MG, Laude H, Dandoy-Dron F: Scrg1 is induced in TSE and brain injuries, and associated with autophagy. Eur J Neurosci 2005, 22:133-146.

Dumpitak C, Beekes M, Weinmann N, Metzger S, Winklhofer KF, Tatzelt J, Riesner D: The polysaccharide scaffold of PrP 27-30 is a common compound of natural prions and consists of alpha-linked polyglucose. Biol Chem 2005, 386:1149-1155.

Eloit M, Adjou K, Coulpier M, Fontaine JJ, Hamel R, Lilin T, Messiaen S, Andreoletti O, Baron T, Bencsik A, Biacabe AG, Beringue V, Laude H, Le Dur A, Vilotte JL, Comoy E, Deslys JP, Grassi J, Simon S, Lantier F, Sarradin P: BSE agent signatures in a goat. Vet Rec 2005, 156:523-524.

Engelstein R, Grigoriadis N, Greig NH, Ovadia H, Gabizon R: Inhibition of P53-related apoptosis had no effect on PrP(Sc) accumulation and prion disease incubation time. Neurobiol Dis 2005, 18:282-285.

Ersdal C, Ulvund MJ, Espenes A, Benestad SL, Sarradin P, Landsverk T: Mapping PrPSc propagation in experimental and natural scrapie in sheep with different PrP genotypes. Vet Pathol 2005, 42:258-274.

Etessami R, Chaumontet C, Laude H, Vilette D: Scratch-wounding renders cultivated cells less permissive to prion infection. Biochem Biophys Res Commun 2005, 330:5-10.

Feraudet C, Morel N, Simon S, Volland H, Frobert Y, Creminon C, Vilette D, Lehmann S, Grassi J: Screening of 145 anti-PrP monoclonal antibodies for their capacity to inhibit PrPSc replication in infected cells. J Biol Chem 2005, 280:11247-11258.

Fevrier B, Laude H, Raposo G, Vilette D: [Exosomes: carriers of prions?]. Med Sci (Paris) 2005, 21:132-133.

Fevrier B, Vilette D, Laude H, Raposo G: Exosomes: a bubble ride for prions? Traffic 2005, 6:10-17.

Fioriti L, Dossena S, Stewart LR, Stewart RS, Harris DA, Forloni G, Chiesa R: Cytosolic prion protein (PrP) is not toxic in N2a cells and primary neurons expressing pathogenic PrP mutations. J Biol Chem 2005, 280:11320-11328.

Fioriti L, Quaglio E, Massignan T, Colombo L, Stewart RS, Salmona M, Harris DA, Forloni G, Chiesa R: The neurotoxicity of prion protein (PrP) peptide 106-126 is independent of the expression level of PrP and is not mediated by abnormal PrP species. Mol Cell Neurosci 2005, 28:165-176.

Freixes M, Rodriguez A, Dalfo E, Ferrer I: Oxidation, glycoxidation, lipoxidation, nitration, and responses to oxidative stress in the cerebral cortex in Creutzfeldt-Jakob disease. Neurobiol Aging 2005.

Galvan C, Camoletto PG, Dotti CG, Aguzzi A, Ledesma MD: Proper axonal distribution of PrP(C) depends on cholesterol-sphingomyelin-enriched membrane domains and is developmentally regulated in hippocampal neurons. Mol Cell Neurosci 2005, 30:304-315.

Gavier-Widen D, Stack MJ, Baron T, Balachandran A, Simmons M: Diagnosis of transmissible spongiform encephalopathies in animals: a review. J Vet Diagn Invest 2005, 17:509-527.

Gavin R, Braun N, Nicolas O, Parra B, Urena JM, Mingorance A, Soriano E, Torres JM, Aguzzi A, del Rio JA: PrP(106-126) activates neuronal intracellular kinases and Egr1 synthesis through activation of NADPH-oxidase independently of PrPc. FEBS Lett 2005, 579:4099-4106.

Gelpi E, Kovacs GG, Strobel T, Koperek O, Voigtlander T, Liberski PP, Budka H: Prion disease with a 144 base pair insertion: unusual cerebellar prion protein immunoreactivity. Acta Neuropathol (Berl) 2005, 110:513-519.

Giese A, Buchholz M, Herms J, Kretzschmar HA: Mouse brain synaptosomes accumulate copper-67 efficiently by two distinct processes independent of cellular prion protein. J Mol Neurosci 2005, 27:347-354.

Glatzel M, Mohajeri MH, Poirier R, Nitsch RM, Schwarz P, Lu B, Aguzzi A: No influence of amyloid-beta-degrading neprilysin activity on prion pathogenesis. J Gen Virol 2005, 86:1861-1867.

Glatzel M, Stoeck K, Seeger H, Luhrs T, Aguzzi A: Human prion diseases: molecular and clinical aspects. Arch Neurol 2005, 62:545-552.

Golanska E, Hulas-Bigoszewska K, Sikorska B, Liberski PP: [Analyses of 14-3-3 protein in the cerebrospinal fluid in Creutzfeldt-Jakob disease. Preliminary report]. Neurol Neurochir Pol 2005, 39:358-365.

Goldmann W, Baylis M, Chihota C, Stevenson E, Hunter N: Frequencies of PrP gene haplotypes in British sheep flocks and the implications for breeding programmes. J Appl Microbiol 2005, 98:1294-1302.

Gonzalez L, Martin S, Houston FE, Hunter N, Reid HW, Bellworthy SJ, Jeffrey M: Phenotype of disease-associated PrP accumulation in the brain of bovine spongiform encephalopathy experimentally infected sheep. J Gen Virol 2005, 86:827-838.

Greenwood AD, Horsch M, Stengel A, Vorberg I, Lutzny G, Maas E, Schadler S, Erfle V, Beckers J, Schatzl H, Leib-Mosch C: Cell line dependent RNA expression profiles of prion-infected mouse neuronal cells. J Mol Biol 2005, 349:487-500.

Gretzschel A, Buschmann A, Eiden M, Ziegler U, Luhken G, Erhardt G, Groschup MH: Strain typing of German transmissible spongiform encephalopathies field cases in small ruminants by biochemical methods. J Vet Med B Infect Dis Vet Public Health 2005, 52:55-63.

Grobben AH, Steele PJ, Somerville RA, Taylor DM, Schreuder BE: Inactivation of the BSE agent by the heat and pressure process for manufacturing gelatine. Vet Rec 2005, 157:277-281.

Hafezparast M, Brandner S, Linehan J, Martin JE, Collinge J, Fisher EM: Prion disease incubation time is not affected in mice heterozygous for a dynein mutation. Biochem Biophys Res Commun 2005, 326:18-22.

Halliday S, Houston F, Hunter N: Expression of PrPC on cellular components of sheep blood. J Gen Virol 2005, 86:1571-1579.

Heikenwalder M, Zeller N, Seeger H, Prinz M, Klohn PC, Schwarz P, Ruddle NH, Weissmann C, Aguzzi A: Chronic lymphocytic inflammation specifies the organ tropism of prions. Science 2005, 307:1107-1110.

Herzog C, Riviere J, Lescoutra-Etchegaray N, Charbonnier A, Leblanc V, Sales N, Deslys JP, Lasmezas CI: PrPTSE distribution in a primate model of variant, sporadic, and iatrogenic Creutzfeldt-Jakob disease. J Virol 2005, 79:14339-14345.

Hijazi N, Kariv-Inbal Z, Gasset M, Gabizon R: PrPSc incorporation to cells requires endogenous glycosaminoglycan expression. J Biol Chem 2005, 280:17057-17061.

Hirsch N, Beckett A, Collinge J, Scaravilli F, Tabrizi S, Berry S: Lymphocyte contamination of laryngoscope blades--a possible vector for transmission of variant Creutzfeldt-Jakob disease. Anaesthesia 2005, 60:664-667.

Hosszu LL, Wells MA, Jackson GS, Jones S, Batchelor M, Clarke AR, Craven CJ, Waltho JP, Collinge J: Definable equilibrium states in the folding of human prion protein. Biochemistry 2005, 44:16649-16657.

Jackson GS, McKintosh E, Flechsig E, Prodromidou K, Hirsch P, Linehan J, Brandner S, Clarke AR, Weissmann C, Collinge J: An enzyme-detergent method for effective prion decontamination of surgical steel. J Gen Virol 2005, 86:869-878.

Jacobi C, Arlt S, Reiber H, Westner I, Kretzschmar HA, Poser S, Zerr I: Immunoglobulins and virus-specific antibodies in patients with Creutzfeldt-Jakob disease. Acta Neurol Scand 2005, 111:185-190.

Jansen C, Houben MP, Hoff JI, Sanchez-Juan P, Rozemuller AJ, van Duijn CM: [The first patient with the new variant of Creutzfeldt-Jakob's disease in The Netherlands]. Ned Tijdschr Geneeskd 2005, 149:2949-2954.

Jew S, Schatzl HM: Prion: gene, structure, and species barrier. J Am Osteopath Assoc 2005, 105:23.

Joiner S, Linehan JM, Brandner S, Wadsworth JD, Collinge J: High levels of disease related prion protein in the ileum in variant Creutzfeldt-Jakob disease. Gut 2005, 54:1506-1508.

Jones M, Head MW, Connolly JG, Farquhar CF, Hornsey VS, Pepper DS, MacGregor IR: Purification of normal cellular prion protein from human platelets and the formation of a high molecular weight prion protein complex following platelet activation. Biochem Biophys Res Commun 2005, 335:48-56.

Jones S, Batchelor M, Bhelt D, Clarke AR, Collinge J, Jackson GS: Recombinant prion protein does not possess SOD-1 activity. Biochem J 2005, 392:309-312.

Kariv-Inbal Z, Halimi M, Dayan Y, Engelstein R, Gabizon R: Characterization of light chain immunoglobulin in urine from animals and humans infected with prion diseases. J Neuroimmunol 2005, 162:12-18.

Khalili-Shirazi A, Quaratino S, Londei M, Summers L, Tayebi M, Clarke AR, Hawke SH, Jackson GS, Collinge J: Protein conformation significantly influences immune responses to prion protein. J Immunol 2005, 174:3256-3263.

Khalili-Shirazi A, Summers L, Linehan J, Mallinson G, Anstee D, Hawke S, Jackson GS, Collinge J: PrP glycoforms are associated in a strain-specific ratio in native PrPSc. J Gen Virol 2005, 86:2635-2644.

Kovacs GG, Preusser M, Strohschneider M, Budka H: Subcellular localization of disease-associated prion protein in the human brain. Am J Pathol 2005, 166:287-294.

Kovacs GG, Puopolo M, Ladogana A, Pocchiari M, Budka H, van Duijn C, Collins SJ, Boyd A, Giulivi A, Coulthart M, Delasnerie-Laupretre N, Brandel JP, Zerr I, Kretzschmar HA, de Pedro-Cuesta J, Calero-Lara M, Glatzel M, Aguzzi A, Bishop M, Knight R, Belay G, Will R, Mitrova E: Genetic prion disease: the EUROCJD experience. Hum Genet 2005, 118:166-174.

Krebs B, Lederer RM, Windl O, Grasbon-Frodl EM, Zerr I, Kretzschmar HA: Creutzfeldt-Jakob disease associated with an R148H mutation of the prion protein gene. Neurogenetics 2005, 6:97-100.

Kristiansen M, Messenger MJ, Klohn PC, Brandner S, Wadsworth JD, Collinge J, Tabrizi SJ: Disease-related prion protein forms aggresomes in neuronal cells leading to caspase activation and apoptosis. J Biol Chem 2005, 280:38851-38861.

Ladogana A, Puopolo M, Croes EA, Budka H, Jarius C, Collins S, Klug GM, Sutcliffe T, Giulivi A, Alperovitch A, Delasnerie-Laupretre N, Brandel JP, Poser S, Kretzschmar H, Rietveld I, Mitrova E, Cuesta Jde P, Martinez-Martin P, Glatzel M, Aguzzi A, Knight R, Ward H, Pocchiari M, van Duijn CM, Will RG, Zerr I: Mortality from Creutzfeldt-Jakob disease and related disorders in Europe, Australia, and Canada. Neurology 2005, 64:1586-1591.

Ladogana A, Puopolo M, Poleggi A, Almonti S, Mellina V, Equestre M, Pocchiari M: High incidence of genetic human transmissible spongiform encephalopathies in Italy. Neurology 2005, 64:1592-1597.

Laffont-Proust I, Faucheux BA, Hassig R, Sazdovitch V, Simon S, Grassi J, Hauw JJ, Moya KL, Haik S: The N-terminal cleavage of cellular prion protein in the human brain. FEBS Lett 2005, 579:6333-6337.

Lasmezas CI, Comoy E, Hawkins S, Herzog C, Mouthon F, Konold T, Auvre F, Correia E, Lescoutra-Etchegaray N, Sales N, Wells G, Brown P, Deslys JP: Risk of oral infection with bovine spongiform encephalopathy agent in primates. Lancet 2005, 365:781-783.

Le Dur A, Beringue V, Andreoletti O, Reine F, Lai TL, Baron T, Bratberg B, Vilotte JL, Sarradin P, Benestad SL, Laude H: A newly identified type of scrapie agent can naturally infect sheep with resistant PrP genotypes. Proc Natl Acad Sci U S A 2005, 102:16031-16036.

Leffers KW, Wille H, Stohr J, Junger E, Prusiner SB, Riesner D: Assembly of natural and recombinant prion protein into fibrils. Biol Chem 2005, 386:569-580.

Lehmann S: Prion propagation in cell culture. Methods Mol Biol 2005, 299:227-234.

Levin J, Bertsch U, Kretzschmar H, Giese A: Single particle analysis of manganese-induced prion protein aggregates. Biochem Biophys Res Commun 2005, 329:1200-1207.

Liberski PP, Streichenberger N, Giraud P, Soutrenon M, Meyronnet D, Sikorska B, Kopp N: Ultrastructural pathology of prion diseases revisited: brain biopsy studies. Neuropathol Appl Neurobiol 2005, 31:88-96.

Ligios C, Sigurdson CJ, Santucciu C, Carcassola G, Manco G, Basagni M, Maestrale C, Cancedda MG, Madau L, Aguzzi A: PrPSc in mammary glands of sheep affected by scrapie and mastitis. Nat Med 2005, 11:1137-1138.

Mabbott NA, Mohand J, Bruce ME: The role of the immune system in TSE agent neuroinvasion. In In Prions: Food and Drug Safety. Edited by Kitamoto T: Springer-Verlag; 2005:119-139.

Magri G, Clerici M, Dall'Ara P, Biasin M, Caramelli M, Casalone C, Giannino ML, Longhi R, Piacentini L, Della Bella S, Gazzuola P, Martino PA, Pollera C, Puricelli M, Servida F, Crescio I, Boasso A, Ponti W, Poli G: Decrease in pathology and progression of scrapie after immunisation with synthetic prion protein peptides in hamsters. Vaccine 2005, 23:2862-2868.

Maignien T, Shakweh M, Calvo P, Marce D, Sales N, Fattal E, Deslys JP, Couvreur P, Lasmezas CI: Role of gut macrophages in mice orally contaminated with scrapie or BSE. Int J Pharm 2005, 298:293-304.

Mallucci G, Collinge J: Rational targeting for prion therapeutics. Nat Rev Neurosci 2005, 6:23-34.

Manson J, Barron R, Hart P, Tuzi N, Bishop M: The role of host PrP in control of incubation time. In In Prions: Food and Drug Safety. Edited by T K: Springer-Verlag; 2005:109-118.

Manson JC, Barron RM: The transmissible spongiform encephalopathies. In In Molecular Pathogenesis of Viral Infections. Society for General Microbiology Symposia. Edited by Press CU; 2005:137-158.

Martin S, Gonzalez L, Chong A, Houston FE, Hunter N, Jeffrey M: Immunohistochemical characteristics of disease-associated PrP are not altered by host genotype or route of inoculation following infection of sheep with bovine spongiform encephalopathy. J Gen Virol 2005, 86:839-848.

Masel J, Genoud N, Aguzzi A: Efficient inhibition of prion replication by PrP-Fc(2) suggests that the prion is a PrP(Sc) oligomer. J Mol Biol 2005, 345:1243-1251.

Matucci A, Zanusso G, Gelati M, Farinazzo A, Fiorini M, Ferrari S, Andrighetto G, Cestari T, Caramelli M, Negro A, Morbin M, Chiesa R, Monaco S, Tridente G: Analysis of mammalian scrapie protein by novel monoclonal antibodies recognizing distinct prion protein glycoforms: an immunoblot and immunohistochemical study at the light and electron microscopic levels. Brain Res Bull 2005, 65:155-162.

Mayer-Sonnenfeld T, Zeigler M, Halimi M, Dayan Y, Herzog C, Lasmezas CI, Gabizon R: The metabolism of glycosaminoglycans is impaired in prion diseases. Neurobiol Dis 2005, 20:738-743.

McCutcheon S, Hunter N, Houston F: Use of a new immunoassay to measure PrP Sc levels in scrapie-infected sheep brains reveals PrP genotype-specific differences. J Immunol Methods 2005, 298:119-128.

Mead S, Prout K, Collinge J: Questionnaire to reduce the risk of iatrogenic prion disease transmission. J Hosp Infect 2005, 60:378-379.

Meissner B, Westner IM, Kallenberg K, Krasnianski A, Bartl M, Varges D, Bosenberg C, Kretzschmar HA, Knauth M, Schulz-Schaeffer WJ, Zerr I: Sporadic Creutzfeldt-Jakob disease: clinical and diagnostic characteristics of the rare VV1 type. Neurology 2005, 65:1544-1550.

Mentler M, Weiss A, Grantner K, del Pino P, Deluca D, Fiori S, Renner C, Klaucke WM, Moroder L, Bertsch U, Kretzschmar HA, Tavan P, Parak FG: A new method to determine the structure of the metal environment in metalloproteins: investigation of the prion protein octapeptide repeat Cu(2+) complex. Eur Biophys J 2005, 34:97-112.

Mohan J, Bruce ME, Mabbott NA: Follicular dendritic cell dedifferentiation reduces scrapie susceptibility following inoculation via the skin. Immunology 2005, 114:225-234.

Mohan J, Bruce ME, Mabbott NA: Neuroinvasion by scrapie following inoculation via the skin is independent of migratory Langerhans cells. J Virol 2005, 79:1888-1897.

Mohan J, Hopkins J, Mabbott NA: Skin-derived dendritic cells acquire and degrade the scrapie agent following in vitro exposure. Immunology 2005, 116:122-133.

Monleon E, Monzon M, Hortells P, Bolea R, Acin C, Vargas F, Badiola JJ: Approaches to Scrapie diagnosis by applying immunohistochemistry and rapid tests on central nervous and lymphoreticular systems. J Virol Methods 2005, 125:165-171.

Moore RA, Vorberg I, Priola SA: Species barriers in prion diseases--brief review. Arch Virol Suppl 2005:187-202.

Moum T, Olsaker I, Hopp P, Moldal T, Valheim M, Benestad SL: Polymorphisms at codons 141 and 154 in the ovine prion protein gene are associated with scrapie Nor98 cases. J Gen Virol 2005, 86:231-235.

Nawrocka-Kunecka A, Papierz W, Liberski PP: Complement factors C1q and C3b in brains with Creutzfeldt-Jakob disease. Pol J Pathol 2005, 56:127-129.

Nikles D, Bach P, Boller K, Merten CA, Montrasio F, Heppner FL, Aguzzi A, Cichutek K, Kalinke U, Buchholz CJ: Circumventing tolerance to the prion protein (PrP): vaccination with PrP-displaying retrovirus particles induces humoral immune responses against the native form of cellular PrP. J Virol 2005, 79:4033-4042.

Nordstrom EK, Luhr KM, Ibanez C, Kristensson K: Inhibitors of the mitogen-activated protein kinase kinase 1/2 signaling pathway clear prion-infected cells from PrPSc. J Neurosci 2005, 25:8451-8456.

Nunziante M, Kehler C, Maas E, Kassack MU, Groschup M, Schatzl HM: Charged bipolar suramin derivatives induce aggregation of the prion protein at the cell surface and inhibit PrPSc replication. J Cell Sci 2005, 118:4959-4973.

O'Neill GT, Cairns D, Toovey L, Goldmann W, Hunter N: New ovine PrP gene haplotypes as a result of single nucleotide polymorphisms in the PrP gene promoter. J Anim Breed Genet 2005, 122:86-94.

Paisley LG, Hostrup-Pedersen J: A quantitative assessment of the BSE risk associated with fly ash and slag from the incineration of meat-and-bone meal in a gas-fired power plant in Denmark. Prev Vet Med 2005, 68:263-275.

Papassotiropoulos A, Wollmer MA, Aguzzi A, Hock C, Nitsch RM, de Quervain DJ: The prion gene is associated with human long-term memory. Hum Mol Genet 2005, 14:2241-2246.

Petersen RB, Siedlak SL, Lee HG, Kim YS, Nunomura A, Tagliavini F, Ghetti B, Cras P, Moreira PI, Castellani RJ, Guentchev M, Budka H, Ironside JW, Gambetti P, Smith MA, Perry G: Redox metals and oxidative abnormalities in human prion diseases. Acta Neuropathol (Berl) 2005, 110:232-238.

Piening N, Weber P, Giese A, Kretzschmar H: Breakage of PrP aggregates is essential for efficient autocatalytic propagation of misfolded prion protein. Biochem Biophys Res Commun 2005, 326:339-343.

Pimpinelli F, Lehmann S, Maridonneau-Parini I: The scrapie prion protein is present in flotillin-1-positive vesicles in central- but not peripheral-derived neuronal cell lines. Eur J Neurosci 2005, 21:2063-2072.

Polymenidou M, Stoeck K, Glatzel M, Vey M, Bellon A, Aguzzi A: Coexistence of multiple PrPSc types in individuals with Creutzfeldt-Jakob disease. Lancet Neurol 2005, 4:805-814.

Puoti G, Giaccone G, Mangieri M, Limido L, Fociani P, Zerbi P, Suardi S, Rossi G, Iussich S, Capobianco R, Di Fede G, Marcon G, Cotrufo R, Filippini G, Bugiani O, Tagliavini F: Sporadic Creutzfeldt-Jakob disease: the extent of microglia activation is dependent on the biochemical type of PrPSc. J Neuropathol Exp Neurol 2005, 64:902-909.

Radovanovic I, Braun N, Giger OT, Mertz K, Miele G, Prinz M, Navarro B, Aguzzi A: Truncated prion protein and Doppel are myelinotoxic in the absence of oligodendrocytic PrPC. J Neurosci 2005, 25:4879-4888.

Revault M, Quiquampoix H, Baron MH, Noinville S: Fate of prions in soil: trapped conformation of full-length ovine prion protein induced by adsorption on clays. Biochim Biophys Acta 2005, 1724:367-374.

Rezaei H, Eghiaian F, Perez J, Doublet B, Choiset Y, Haertle T, Grosclaude J: Sequential generation of two structurally distinct ovine prion protein soluble oligomers displaying different biochemical reactivities. J Mol Biol 2005, 347:665-679.

Righetti PG, Castagna A, Antonucci F, Piubelli C, Cecconi D, Campostrini N, Rustichelli C, Antonioli P, Zanusso G, Monaco S, Lomas L, Boschetti E: Proteome analysis in the clinical chemistry laboratory: myth or reality? Clin Chim Acta 2005, 357:123-139.

Rigter A, Bossers A: Sheep scrapie susceptibility-linked polymorphisms do not modulate the initial binding of cellular to disease-associated prion protein prior to conversion. J Gen Virol 2005, 86:2627-2634.

Rodriguez A, Freixes M, Dalfo E, Martin M, Puig B, Ferrer I: Metabotropic glutamate receptor/phospholipase C pathway: a vulnerable target to Creutzfeldt-Jakob disease in the cerebral cortex. Neuroscience 2005, 131:825-832.

Rodriguez MM, Peoc'h K, Haik S, Bouchet C, Vernengo L, Manana G, Salamano R, Carrasco L, Lenne M, Beaudry P, Launay JM, Laplanche JL: A novel mutation (G114V) in the prion protein gene in a family with inherited prion disease. Neurology 2005, 64:1455-1457.

Roeber S, Krebs B, Neumann M, Windl O, Zerr I, Grasbon-Frodl EM, Kretzschmar HA: Creutzfeldt-Jakob disease in a patient with an R208H mutation of the prion protein gene (PRNP) and a 17-kDa prion protein fragment. Acta Neuropathol (Berl) 2005, 109:443-448.

Rosicarelli B, Serafini B, Sbriccoli M, Lu M, Cardone F, Pocchiari M, Aloisi F: Migration of dendritic cells into the brain in a mouse model of prion disease. J Neuroimmunol 2005, 165:114-120.

Russmann H, Vingerhoets F, Miklossy J, Maeder P, Glatzel M, Aguzzi A, Bogousslavsky J: Sporadic Creutzfeldt-Jakob disease: a comparison of pathological findings and diffusion weighted imaging. J Neurol 2005, 252:338-342.

Sabuncu E, Paquet S, Chapuis J, Moudjou M, Lai TL, Grassi J, Baron U, Laude H, Vilette D: Prion proteins from susceptible and resistant sheep exhibit some distinct cell biological features. Biochem Biophys Res Commun 2005, 337:791-798.

Safar JG, Kellings K, Serban A, Groth D, Cleaver JE, Prusiner SB, Riesner D: Search for a prion-specific nucleic acid. J Virol 2005, 79:10796-10806.

Salmona M, Capobianco R, Colombo L, De Luigi A, Rossi G, Mangieri M, Giaccone G, Quaglio E, Chiesa R, Donati MB, Tagliavini F, Forloni G: Role of plasminogen in propagation of scrapie. J Virol 2005, 79:11225-11230.

Sarafoff NI, Bieschke J, Giese A, Weber P, Bertsch U, Kretzschmar HA: Automated PrPres amplification using indirect sonication. J Biochem Biophys Methods 2005, 63:213-221.

Seeger H, Heikenwalder M, Zeller N, Kranich J, Schwarz P, Gaspert A, Seifert B, Miele G, Aguzzi A: Coincident scrapie infection and nephritis lead to urinary prion excretion. Science 2005, 310:324-326.

Sharpe A, McElroy M, Langeveld JP, Bassett H, O'Donoghue AM, Sweeney T: Immunohistochemical studies of scrapie archival material from Irish ARQ/ARQ sheep for evidence of bovine spongiform encephalopathy-derived disease. Res Vet Sci 2005, 79:29-35.

Sigurdson C, Glatzel M, Aguzzi A: Comment on "Failure to detect prion protein (PrPres) by immunohistochemistry in striated muscle tissues of animals experimentally inoculated with agents of transmissible spongiform encephalopathy". Vet Pathol 2005, 42:107.

Sigurdson C, Polymenidou M, Aguzzi A: Reconstructing prions: fibril assembly from simple yeast to complex mammals. Neurodegener Dis 2005, 2:1-5.

Somerville RA, Hamilton S, Fernie K: Transmissible spongiform encephalopathy strain, PrP genotype and brain region all affect the degree of glycosylation of PrPSc. J Gen Virol 2005, 86:241-246.

Soto C, Anderes L, Suardi S, Cardone F, Castilla J, Frossard MJ, Peano S, Saa P, Limido L, Carbonatto M, Ironside J, Torres JM, Pocchiari M, Tagliavini F: Pre-symptomatic detection of prions by cyclic amplification of protein misfolding. FEBS Lett 2005, 579:638-642.

Steinacker P, Schwarz P, Reim K, Brechlin P, Jahn O, Kratzin H, Aitken A, Wiltfang J, Aguzzi A, Bahn E, Baxter HC, Brose N, Otto M: Unchanged survival rates of 14-3-3gamma knockout mice after inoculation with pathological prion protein. Mol Cell Biol 2005, 25:1339-1346.

Stork M, Giese A, Kretzschmar HA, Tavan P: Molecular dynamics simulations indicate a possible role of parallel beta-helices in seeded aggregation of poly-Gln. Biophys J 2005, 88:2442-2451.

Thuring CM, van Keulen LJ, Langeveld JP, Vromans ME, van Zijderveld FG, Sweeney T: Immunohistochemical distinction between preclinical bovine spongiform encephalopathy and scrapie infection in sheep. J Comp Pathol 2005, 132:59-69.

Trieschmann L, Navarrete Santos A, Kaschig K, Torkler S, Maas E, Schatzl H, Bohm G: Ultra-sensitive detection of prion protein fibrils by flow cytometry in blood from cattle affected with bovine spongiform encephalopathy. BMC Biotechnol 2005, 5:26.

Tschampa HJ, Kallenberg K, Urbach H, Meissner B, Nicolay C, Kretzschmar HA, Knauth M, Zerr I: MRI in the diagnosis of sporadic Creutzfeldt-Jakob disease: a study on inter-observer agreement. Brain 2005, 128:2026-2033.

Uelhoff A, Tatzelt J, Aguzzi A, Winklhofer KF, Haass C: A pathogenic PrP mutation and doppel interfere with polarized sorting of the prion protein. J Biol Chem 2005, 280:5137-5140.

Unterberger U, Voigtlander T, Budka H: Pathogenesis of prion diseases. Acta Neuropathol (Berl) 2005, 109:32-48.

Vargas F, Bolea R, Monleon E, Acin C, Vargas A, De Blas I, Lujan L, Badiola JJ: Clinical characterisation of natural scrapie in a native Spanish breed of sheep. Vet Rec 2005, 156:318-320.

Vasina EN, Dejardin P, Rezaei H, Grosclaude J, Quiquampoix H: Fate of prions in soil: adsorption kinetics of recombinant unglycosylated ovine prion protein onto mica in laminar flow conditions and subsequent desorption. Biomacromolecules 2005, 6:3425-3432.

Vassallo N, Herms J, Behrens C, Krebs B, Saeki K, Onodera T, Windl O, Kretzschmar HA: Activation of phosphatidylinositol 3-kinase by cellular prion protein and its role in cell survival. Biochem Biophys Res Commun 2005, 332:75-82.

Veerhuis R, Boshuizen RS, Morbin M, Mazzoleni G, Hoozemans JJ, Langedijk JP, Tagliavini F, Langeveld JP, Eikelenboom P: Activation of human microglia by fibrillar prion protein-related peptides is enhanced by amyloid-associated factors SAP and C1q. Neurobiol Dis 2005, 19:273-282.

Vetrugno V, Cardinale A, Filesi I, Mattei S, Sy MS, Pocchiari M, Biocca S: KDEL-tagged anti-prion intrabodies impair PrP lysosomal degradation and inhibit scrapie infectivity. Biochem Biophys Res Commun 2005, 338:1791-1797.

Visani E, Agazzi P, Scaioli V, Giaccone G, Binelli S, Canafoglia L, Panzica F, Tagliavini F, Bugiani O, Avanzini G, Franceschetti S: FVEPs in Creutzfeldt-Jacob disease: waveforms and interaction with the periodic EEG pattern assessed by single sweep analysis. Clin Neurophysiol 2005, 116:895-904.

Weissmann C, Aguzzi A: Approaches to therapy of prion diseases. Annu Rev Med 2005, 56:321-344.

Will RG: Commentary: The risk of variant Creutzfeldt-Jakob Disease: reassurance and uncertainty. Int J Epidemiol 2005, 34:52-53.

Windl O, Buchholz M, Neubauer A, Schulz-Schaeffer W, Groschup M, Walter S, Arendt S, Neumann M, Voss AK, Kretzschmar HA: Breaking an absolute species barrier: transgenic mice expressing the mink PrP gene are susceptible to transmissible mink encephalopathy. J Virol 2005, 79:14971-14975.

Wiseman F, Cancellotti E, Manson J: Glycosylation and misfolding of PrP. Biochem Soc Trans 2005, 33:1094-1095.

Wojtera M, Sikorska B, Sobow T, Liberski PP: Microglial cells in neurodegenerative disorders. Folia Neuropathol 2005, 43:311-321.

Xanthopoulos K, Paspaltsis I, Apostolidou V, Petrakis S, Siao CJ, Kalpatsanidis A, Grigoriadis N, Tsaftaris A, Tsirka SE, Sklaviadis T: Tissue plasminogen activator in brain tissues infected with transmissible spongiform encephalopathies. Neurobiol Dis 2005, 20:519-527.

Xiang W, Windl O, Westner IM, Neumann M, Zerr I, Lederer RM, Kretzschmar HA: Cerebral gene expression profiles in sporadic Creutzfeldt-Jakob disease. Ann Neurol 2005, 58:242-257.

Zanusso G, Fiorini M, Farinazzo A, Gelati M, Benedetti MD, Ferrari S, Dalla Libera A, Capaldi S, Monaco HL, Rizzuto N, Monaco S: Phosphorylated 14-3-3zeta protein in the CSF of neuroleptic-treated patients. Neurology 2005, 64:1618-1620.

Zingler VC, Strupp M, Jahn K, Glaser M, Herberger S, Kretzschmar HA, Brandt T: Upbeat nystagmus as the initial clinical sign of Creutzfeldt-Jakob disease. Ann Neurol 2005, 57:607-608.

NeuroPrion Network of Excellence

Prion publications from our partners (2005-2006)

Updated on: 7th of September 2006

Published in 2006

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Published in 2005

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